Older gentleman rubbing irritated eye.
Inflammatory Eye Disease

Types of Inflammatory Eye Diseases

Think inflammation is just about sore knees or stiff hands? Think again. Your eyes are just as vulnerable.

Inflammatory eye diseases are a group of disorders that cause swelling, redness, pain, and vision changes. It might seem like allergies or infection at first, but persistent symptoms point to underlying systemic autoimmune issues that can cause long-term eye damage if untreated. In fact, uveitis, a common form of eye inflammation, accounts for 30,000 new cases of legal blindness annually in the USA and about 10–15% of all cases of total blindness in the country.1

What other common types of inflammatory eye diseases are there? What causes them, and how do they present? Are there any treatments available? We answer all these questions below, plus how infusion therapy at IDYLLIC Infusion Treatment Center can help you find relief and protect your eye health.

What Is Inflammatory Eye Disease?

Inflammatory eye disease is a broad term used to describe a variety of conditions where the immune system mistakenly attacks healthy tissue in the eye. This immune response leads to inflammation, which can affect various parts of the eye, including the uvea, retina, optic nerve, sclera, and more.

These conditions may be isolated to the eyes or associated with systemic diseases like rheumatoid arthritis, lupus, or sarcoidosis.2,3,4

Left untreated, inflammation can damage vital structures of the eye and lead to permanent vision loss.1 Early detection, accurate diagnosis, and appropriate therapy are essential to preserving sight and improving long-term outcomes.

Common Types of Inflammatory Eye Diseases

Inflammatory eye diseases can affect different parts of the eye. Here are the most recognized types:

Uveitis

Uveitis refers to inflammation of the uvea, the middle layer of the eye. It can be classified as anterior (front), intermediate, posterior, or panuveitis (entire uvea). Causes can range from autoimmune conditions to infections or trauma. Symptoms often include pain, light sensitivity, redness, and blurred vision.5

Scleritis

This is inflammation of the sclera, the white outer wall of the eye. It’s frequently associated with autoimmune diseases like rheumatoid arthritis. Scleritis is painful, can cause severe eye redness, and may impair vision if not treated promptly.6

Episcleritis

A milder form than scleritis, episcleritis affects the thin layer of tissue that covers the sclera. It usually presents with localized redness and discomfort.6

Optic Neuritis

Optic neuritis is inflammation of the optic nerve, often tied to multiple sclerosis. It may cause sudden vision loss in one eye, pain with eye movement, and changes in color perception.7

Keratitis

This condition involves inflammation of the cornea. It can result from infections, trauma, or autoimmune responses. Keratitis can cause redness, discharge, pain, and irritation.8

Retinitis

Retinitis is inflammation of the retina, typically from infections like cytomegalovirus (CMV) or autoimmune causes. Symptoms include blurred vision, floaters, and night vision problems.9

Causes and Risk Factors

Inflammatory eye diseases can be caused by a wide range of triggers. Autoimmune conditions such as lupus, rheumatoid arthritis, and ankylosing spondylitis are among the most common culprits.3,2,10 In these cases, the body’s immune system mistakenly attacks its own eye tissues.

Infectious agents like viruses, bacteria, and parasites can also lead to inflammation, especially in individuals with weakened immune systems. Other risk factors include recent eye trauma or surgery, as well as smoking. Sometimes, no direct cause is found, which can complicate treatment and diagnosis.

Understanding the underlying cause is essential for developing an effective treatment plan. That’s why patients often benefit from a multidisciplinary approach that includes ophthalmologists, rheumatologists, alongside their primary care doctor.

Symptoms to Watch For

Inflammatory eye diseases don’t always start with pain, but they nearly always involve changes you shouldn’t ignore. If you’re experiencing any of the following symptoms, it’s time to speak to a specialist:

  • Redness and Pain: One of the most common symptoms. Red eyes accompanied by sharp or throbbing pain can signal inflammation of the deeper tissues.
  • Light Sensitivity (Photophobia): If bright lights suddenly become unbearable, this could point to anterior uveitis or keratitis.
  • Blurred or Diminished Vision: Inflammation can cloud vision or even cause blind spots, especially with optic neuritis or posterior uveitis.
  • Floaters and Flashes: These visual disturbances might suggest inflammation in the vitreous or retina.
  • Eye Discharge or Tearing: Especially in keratitis, excessive tearing or unusual discharge can be a warning sign.
  • Color Changes or Visual Field Loss: If colors appear faded or vision becomes patchy, the optic nerve might be inflamed.

Don’t brush these symptoms off. Getting an early diagnosis can be the difference between quick recovery and long-term complications.

When to Seek Medical Attention

If you notice any of the above symptoms, the first step is to schedule an appointment with your eye doctor. They can determine what is causing your symptoms and may refer you to another specialist to see if your symptoms are related to an underlying systemic disease. Eye inflammation can escalate quickly, so acting fast is key.

If your eye doctor confirms the need for further treatment, the next step is to find a specialist experienced in autoimmune disease. That’s where ARBDA and IDYLLIC Infusion Treatment Center comes in. We work in collaboration with your doctors to provide infusion therapies tailored to treat inflammatory eye disease effectively, targeting the source of inflammation, not just the symptoms.

Treatment Options

Treatment for inflammatory eye diseases is highly individualized and depends on the type and severity of inflammation. Common approaches include:

  • Topical or Oral Corticosteroids: These anti-inflammatory medications can reduce swelling quickly and have been the preferred treatment for many years.11
  • Immunosuppressive Medications: These include methotrexate, azathioprine, or cyclosporine. They’re often prescribed for patients with recurring or chronic disease.11
  • Biologic Agents: In cases where traditional immunosuppressants are ineffective, biologics like infliximab, brand name Remicade®, may be used to precisely target inflammatory pathways.11
  • Antibiotics or Antivirals: When the inflammation stems from an infection, treating the underlying pathogen is essential.

IDYLLIC Infusion Treatment Center provides access to advanced biologics via safe and convenient outpatient infusions under the care of experienced professionals.

Preventive Measures and Eye Care Tips

While some causes of inflammatory eye diseases can’t be prevented, there are steps you can take to reduce your risk and protect your vision. Staying on top of your general health is a great place to start. Chronic conditions like diabetes, high blood pressure, or autoimmune diseases can all affect your eyes, so managing these effectively with your primary care physician is essential.

It’s also important to practice good eye hygiene and safety. Always remove makeup before sleeping, avoid touching your eyes with unwashed hands, wear protective eyewear when needed, and follow your eye doctor’s instructions if you’re a contact lens user.

Don’t skip your regular eye exams, as many inflammatory conditions can be detected early during routine check-ups.

Curious About How Infusion Therapy Can Support Eye Health?

For patients with moderate to severe inflammatory eye disease, especially those linked to autoimmune conditions, infusion therapy can be a game-changer.

This treatment involves delivering medication directly into the bloodstream, allowing for faster, more effective results than long-term oral therapies. Infusion therapy is commonly used for conditions like uveitis or scleritis when conventional treatments aren’t effective in reducing symptoms.

Before starting any infusion therapy, we always recommend discussing your symptoms and treatment options with your primary care physician or eye specialist. If they determine that infusion is right for you, you’ll want to choose a trusted provider. That’s where IDYLLIC Infusion Treatment Center shines.

Our experienced staff and comfortable outpatient environment make treatment as smooth and supportive as possible. We coordinate with your healthcare team to deliver therapies that align with your overall care plan.

Ready to Take the Next Step? Schedule Your Visit with IDYLLIC Today

If you or a loved one is dealing with persistent eye inflammation, don’t wait. At IDYLLIC Infusion Treatment Center, we’re here to provide the advanced, compassionate care you deserve. We partner with referring physicians to create a seamless treatment experience tailored to your needs.

Let’s work together to protect your vision and improve your quality of life. Contact us today to schedule an appointment or learn more about uveitis infusion therapy treatments.


1https://pmc.ncbi.nlm.nih.gov/articles/PMC5904090/

2https://pmc.ncbi.nlm.nih.gov/articles/PMC5489043/

3https://pmc.ncbi.nlm.nih.gov/articles/PMC3395333/

4https://www.ncbi.nlm.nih.gov/books/NBK580538/

5https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/uveitis

6https://www.ncbi.nlm.nih.gov/books/NBK499944/

7https://www.ncbi.nlm.nih.gov/books/NBK557853/

8https://www.ncbi.nlm.nih.gov/books/NBK559014/

9https://www.ncbi.nlm.nih.gov/books/NBK560520/

10https://www.medicalnewstoday.com/articles/ankylosing-spondylitis-eye-health

11https://pmc.ncbi.nlm.nih.gov/articles/PMC3744780/